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Cat. No.	Product Name	Species	Expression System
TMPY-02438	AKR1B1 Protein, Human, Recombinant (His) ALDR1,AR,ADR,aldo-keto reductase family 1, member B1 (aldose...	Human	E. coli
	Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the c...
TMPK-00870	AREG Protein, Mouse, Recombinant (hFc) AR,MGC13647,CRDGF,AREG,Amphiregulin,SDGF,AREGB	Mouse	HEK293 Cells
	Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.
TMPJ-00859	AREG Protein, Human, Recombinant AR,CRDGF,Amphiregulin,Colorectum Cell-Derived Growth Factor,...	Human	E. coli
	Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits...
TMPK-00820	AREG Protein, Human, Recombinant (hFc) SDGF,AR,MGC13647,AREGB,CRDGF,Amphiregulin,AREG	Human	HEK293 Cells
	Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells.

重组蛋白

AKR1B1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02438

Species: Human

Expression System: E. coli

AREG Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00870

Species: Mouse

Expression System: HEK293 Cells

AREG Protein, Human, Recombinant

Cat.No: TMPJ-00859

Species: Human

Expression System: E. coli

AREG Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00820

Species: Human

Expression System: HEK293 Cells

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